Printed biophotonic sensors for blood and tissue oximetry

Organic optoelectronic probe for transmission-mode pulse oximetry.

Reflection-mode pulse oximetry using an organic oximeter probe on a volunteer's wrist.

Oximetry, the technique for determining oxygen saturation, optically measures the light absorption of oxygenated and deoxygenated blood and tissue at two different wavelengths. In 2014, we demonstrated the first all-organic optoelectronic oximeter sensor composed of organic light-emitting diodes (OLEDs) and an organic photodiode (OPD) to accurately measure pulse rate and oxygenation with errors of 1% and 2%, respectively [1]. This transmission-mode probe demonstrated that oximetry can be performed with organic optoelectronics. However, to realize the true potential of organic optoelectronics for oximetry, a reflection-mode operation is essential that allows sensor placement on different parts of the body. After optimizing the sensor design and the printing process, in 2017, we reported a reflection-mode organic oximeter probe and performed blood oxygenation measurements on the wrist [2].

Relevant publications:

  1. All-organic optoelectronic sensor for pulse oximetry Claire M. Lochner*, Yasser Khan*, Adrien Pierre*, and Ana C. Arias Nature Communications, 2014 5, 5745. [Abstract] [Bibtex] [PDF] *Equal contribution. Media Coverage: UC Berkeley Grad News, NSF Science 360 News, UC Berkeley News Center, Phys.org, ScienceDaily, and many more.
  1. Flexible Blade-Coated Multicolor Polymer Light-Emitting Diodes for Optoelectronic Sensors Donggeon Han, Yasser Khan, Jonathan Ting, Simon M. King, Nir Yaacobi-Gross, Martin J. Humphries, Christopher J. Newsome, and Ana C. Arias Advanced Materials, 2017 29, 22. [Abstract] [Bibtex] [PDF]

Last modified: 2018-01-02